Sandalwood oil is perhaps best known in the west as a sweet, warm, rich and woody essential oil used as is for a body fragrance, and as an ingredient in fragrant products such as incense, perfumes, aftershaves and other cosmetics. But the story of sandalwood, the divine essence, goes much further. Sandalwood has been a part of the religious and spiritual traditions of India since prehistory and has been effectively used in traditional medicine for thousands of years.
The nose is not the only place where olfactory receptors occur
Humans have approximately 350 different types of olfactory receptors in the nose. The function of those receptors has also been shown to exist in, for example spermatozoa, the prostate, the intestine and the kidneys. The team from Bochum has now discovered them in keratinocytes cells that form the outermost layer of the skin.
Experiments with cultures of human skin cells
The RUB researchers studied the olfactory receptor that occurs in the skin, namely OR2AT4, and discovered that it is activated by a synthetic sandalwood scent, so-called Sandalore. Sandalwood aroma is frequently used in incense sticks and is a popular component in perfumes. The activated OR2AT4 receptor triggers a calcium-dependent signal pathway. That pathway ensures an increased proliferation and a quicker migration of skin cells processes which typically facilitate wound healing. In collaboration with the Dermatology Department at the University …
Sandalwood oil is rare and expensive and the price is going up rapidly as the Indian government places tighter regulations on its production and export. If you find a Sandalwood that you truly like, buy enough to last you, and then use it sparingly.
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