A pathogen or infectious agent is a biological agent that causes disease or illness to its host. The term is most often used for agents that disrupt the normal physiology of a multicellular animal or plant. There are several substrates and pathways whereby pathogens can invade a host. The human body contains many natural defenses against some of common pathogens in the form of the human immune system and by some “helpful” bacteria present in the human body's normal flora. Today, while many medical advances have been made to safeguard against infection by pathogens, through the use of vaccination, antibiotics and fungicide, pathogens continue to threaten human life.
By Dr. Mercola
Good oral hygiene is even more important than previously thought. Pathogenic microorganisms and their toxins can harm more than just your mouth when they circulate through your bloodstream—they can potentially cause secondary infections and chronic inflammation throughout your body.
The fact that oral pathogens can make their way to distant parts of your anatomy and cause serious problems has been known for many years.
Even dentists would agree that bacteria can pass from your gums into your bloodstream and on to your heart, which is why some still prescribe oral antibiotics to a few select patients with a particularly high risk for endocarditis, particularly if they have gingivitis.
But it appears that the rare case of endocarditis is only the tip of the iceberg. Several studies now show that these oral pathogens—viruses as well as bacteria—may be linked to certain cancers, making it even more important to do take every step possible to ensure your teeth and gums stay healthy.
Poor Oral Health Is a Risk Factor for Oropharyngeal Cancers
The human papillomavirus (HPV), some strains of which are associated with cervical cancer if left untreated for long periods of time, has similarly been linked to vaginal, vulvar, penile, anal, and oropharyngeal cancers (cancers of the throat, tonsils, and base of tongue).
Hence the ridiculous recommendation to vaccinate boys with the notorious HPV vaccine, Gardasil, which is riddled with dangerous side effects and other problems. A new study published in the journal Cancer Prevention Research reports:
“Poor oral health, which includes dental problems and gum disease, is an independent risk factor for oral HPV infection, and by extension, could also contribute to oral cancers.”
In this study, participants with poor oral health had a 56 percent higher rate of HPV infection than those with healthy mouths. Centers for Disease Control and Prevention states that about 60 percent of oropharyngeal cancers are related to HPV, but according to the latest study, it could be as high as 80 percent.
The researchers speculate that good oral hygiene could help prevent HPV infection, thereby lowing your risk for oropharyngeal and other cancers. Human papillomavirus is actually a group of more than 100 viruses. Of those 100, about 40 are sexually transmitted, and 15 of those are the types most often associated with cervical cancers and genital warts.
It is important to note that more than 90 percent of women infected with HPV clear the infection naturally within two years, at which point their cervical cells return to normal. It is only when the HPV virus lingers for many years (that is, becomeschronic) that abnormal cervical cells could turn into cancer.
This is why regularly scheduled PAP smears prevent cervical cancer deaths far more effectively than the HPV vaccine ever will, because they allow a sufficient amount of time to find and treat any cervical abnormalities.
Viruses Cause 15 to 20 Percent of All Cancers
It is interesting to note that HPV isn't the only virus linked to cancer—in fact, it is estimated that 15 to 20 percent of all cancers are caused by viruses! Many viruses trigger cancer by suppressing your immune system and/or altering your genes. The following viruses are known to play a major role in certain types of cancer:
- EBV (Epstein-Barr virus) increases your risk for nasopharyngeal cancer, certain lymphomas and stomach cancer
- Hepatitis B and C are linked to liver cancer
- HIV is associated with invasive cervical cancer, lymphoma, lung cancer, liver cancer, anal cancer, oropharyngeal cancer, skin cancer and Kaposi's sarcoma; Herpes virus 8 is also thought to be involved with almost all cases of Kaposi's sarcoma
Three New Studies Prove Oral Bacteria Can Cause Colorectal Cancer
There is one bacterium that has been causing a great deal of trouble with people's health: Fusobacterium nucleatum, a spindle-shaped anaerobic bacterium commonly found in dental plaque. F. nucleatum is abundant in your mouth and able to coaggregate with other species. Three recent studies have linked F. nucleatum with serious health problems:
- Case Western Reserve University researchers found that some malignant colorectal tumors are caused by F. nucleatum
- Harvard researchers also established a link between F. nucleatum and the initiation of colorectal tumors
- A study in Journal of Obstetrics and Gynecology found that oral F. nucleatum can lead to intrauterine infection and even stillbirth
The first two studies establish an actual causal link between this bacteria and colorectal cancer. The bacteria trigger inflammation and also activate the cancer growth genes and the signals required for angiogenesis to occur (a tumor's blood supply). Normally, F. nucleatum is not prevalent in your gut, but if your microbial balance is off—which can happen in your mouth, as well as in your gut—then it's able to invade and colonize. F. nucleatum has been found in gut mucosal biopsies that show inflammation and in biopsies of colorectal tumors.
The third study discusses an unusual case of a mother losing her baby to stillbirth due to an intrauterine infection, directly resulting from gingivitis. The bacteria moved from her mouth to her uterus because her immune system was weakened by a respiratory infection. Other studies have shown these bacteria to cause stillbirths in mice, but this was the first documented human case.
All of these studies unequivocally show that bacterial imbalances and dysbiosis can contribute to inflammation in your body and activate cancer genes. Therefore, the bacteria in your mouth deserve as much care and attention as the ones in your gut. Not surprisingly, they're interrelated, and as you improve your gut flora, the flora in your mouth improves accordingly. I experienced this myself. When I started consuming fermented vegetables, it only took a few months before I was able to reduce the frequency of my visits to my dental hygienist for a persistent plaque problem.
Another Danger: A Mouthful of Mercury
Besides oral hygiene, which I'll be discussing shortly, there are two other dental-related concerns you may need to address: mercury amalgams and fluoride. The average American has eight mercury amalgams (fillings), falsely described as “silver” fillings. This misleading label has been purposely used to keep you in the dark about the exact composition of the fillings, which are actually about 50 percent mercury. Mercury is a toxic heavy metal that can poison your brain, central nervous system and kidneys. Children and fetuses, whose brains are still developing, are most at risk—but anyone can be adversely impacted.
Mercury is such a potent toxin that just one drop in a lake would poison the lake to the extent that the Environmental Protection Agency (EPA) would ban fishing in it. Yet, they claim that carrying around a mouthful of mercury fillings has no harmful effects. If you have mercury amalgams, it would be advisable to consult a holistic, mercury-free dentist.
Steer Clear of Fluoride in Any Form
If you are using fluoridated toothpaste, you may want to consider tossing it out and replacing it it with a safe one. In the mornings, you could use toothpaste containing calcium and phosphate salts, or even hydroxyapatite, which can help remineralize your teeth. Baking soda will help promote beneficial bacteria in your mouth by neutralizing the acid that pathogenic bacteria thrive in. I use an oral irrigator with baking soda twice a day and follow with coconut oil pulling for 20 minutes.
Fluoride is of little or no benefit to your teeth and poses serious health risks, including immune dysfunction, endocrine disruption, increased risk of fractures, arthritis, infertility, and many more.
Toothpaste isn't the only source of fluoride—it is present in growing numbers of non-organic foods from pesticide residue (including iceberg lettuce). And fluoride continues to be added to many municipal water supplies in the United States. Water fluoridation has come under increasing scrutiny as health concerns, lack of efficacy in preventing tooth decay and ethical issues of administering chemicals via the water supply have surfaced. For more information on fluoride, please watch the presentation by Michael Connett, an attorney with the Fluoride Action Network in this previous article.
Four Strategies for Improving Your Oral Health
The latest research uncovering the connection between the microorganisms in your mouth and cancer make it extraordinarily clear that oral hygiene is a necessary prerequisite if you want to be healthy. Major problems can result from the overgrowth of opportunistic oral pathogens, including oropharyngeal cancers, colorectal cancer, and if you're an expectant mother, even the tragedy of stillbirth. In addition to avoiding fluoride and mercury fillings, my top four recommendations for optimizing your oral health are as follows:
- Consume a traditional diet: fresh fruits and vegetables, grass-pastured meats, poultry, eggs, and dairy; nuts and seeds; minimal consumption of sugar and processed food
- Add in some naturally fermented foods, such as sauerkraut, pickles, kimchee, yogurt, kefir
- Proper brushing and flossing
- Oil pulling
A traditional diet will help balance both your oral and gastrointestinal flora, but it may not be enough to guarantee perfect oral health. I've struggled with plaque for years, and it wasn't until I added fermented foods and oil pulling that I began to make progress with the problem. The addition of fermented foods decreased my plaque by 50 percent and made it much softer, and the oil pulling has improved it further.