The study was conducted by UCLA researchers. They found that combining resveratrol with a common acne medication, benzoyl peroxide, may enhance the drug's ability to kill the bacteria and could translate into new treatments. “We initially thought that since actions of the two compounds are opposing, the combination should cancel the other out, but they didn't,” said Dr. Emma Taylor, the study's first author and an assistant clinical professor of medicine in the division of dermatology at the David Geffen School of Medicine at UCLA, in a press statement. “This study demonstrates that combining an oxidant and an antioxidant may enhance each other and help sustain bacteria-fighting activity over a longer period of time.” Researchers found that though benzoyl peroxide was also capable of killing the bacteria initially, the effect was only short lived. Contrarily, resveratrol didn't have a strong killing ability but the effect lasted longer.
The team at the University of California at Los Angeles have demonstrated also found that combining resveratrol with a common acne medication, benzoyl peroxide, could enhance the drugs effectiveness.
Published in the journal Dermatology and Therapy, the early lab findings demonstrated that resveratrol and benzoyl peroxide attack the acne bacteria, called Propionibacterium acnes, in different ways.
Resveratrol which is found naturally in red grapes, red wine, peanuts and some berries is the same substance that has prompted some doctors to recommend that adults drink red wine for its heart-health properties. The antioxidant stops the formation of free radicals, which cause cell and tissue damage. Benzoyl peroxide is an oxidant that works by creating free radicals that kill the acne bacteria.
We initially thought that since actions of the two compounds are opposing, the combination should cancel the other out, but they didnt, said Dr. Emma Taylor, the studys first author and …
The antioxidant stops the formation of free radicals, which cause cell and tissue damage. The team grew colonies of the bacteria that causes acne and then added various concentrations of resveratrol and benzoyl peroxide, both alone and together. The researchers monitored the cultures for bacterial growth or killing for 10 days. Surprisingly, the two compounds together proved the most effective in reducing bacteria count.
‘It was like combining the best of both worlds and offering a two-pronged attack on the bacteria,’ added senior study author Jenny Kim, professor of clinical medicine in the division of dermatology, UCLA. ‘We hope that our findings lead to a new class of acne therapies that centre on antioxidants such as resveratrol,’ researchers concluded.
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