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  • Tenapanor Can Lower Salt Intake Without Any Dietary Changes

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    A new drug may soon be able to solve the growing problem of excess sodium consumption by lowering an individual’s salt absorption without affecting his or her diet. The medication could potentially help the millions of Americans who suffer from chronic kidney disease (CKD) and hypertension, but who have a hard time adhering to a low-sodium diet.

    Sodium: An important dietary element that the body needs to function.  But too much of the chemical can potentially be deadly.

    Given current diet trends, a significant majority of Americans consume too much sodium from their food, contributing to an overall increase in cardiovascular disease and poor kidney function.  But soon, a new drug may be able to solve this growing problem – by lowering an individual’s salt absorption without affecting his or her diet.

    The medication could potentially help the millions of Americans who suffer from chronic kidney disease (CKD) and hypertension, but who have a hard time adhering to a low-sodium diet.

    Developed by researchers at drug manufacturer Ardelyx, the drug, tenapanor, works by blocking a membrane transporter called NH3, which is responsible for most of the reuptake of sodium in the body.  By inhibiting this protein, the majority of sodium is prevented from seeping into the bloodstream and instead remains …

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    michael

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